New research article - Total body irradiation (TBI)...

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Congratulations to Dr Yvonne Zissiadis, together with medical physicists Kirsty Symons, Colm Morrison, Simon Woodings, and senior radiation therapist Jason Parry, on the publication of their research article Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle3 treatment planning system and Elekta Agility™ linac in the Journal of Applied Clinical Medical Physics.

Total body irradiation (TBI) is used in the management of hematologic malignancies prior to the transplantation of hematopoietic or bone marrow stem cells. The combination of radiation and chemotherapy kills the malignant cells, increasing the likelihood of a successful transplant and suppresses the recipient's immune system to prevent immunologic rejection.

This study demonstrated the feasibility of achieving clinically acceptable volumetric modulated arc therapy (VMAT) TBI plans with the Pinnacle3 treatment planning system and accurate delivery using an Elekta Agility™ linac. The advantages of this technique include improved patient comfort and positioning reproducibility during treatment, accurate 3D dose information, and the ability to selectively spare organs at risk.

The full paper can be accessed here.

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